The Association Between Body Mass Index and Carpal Tunnel Syndrome Among Medical Students of Universitas Pelita Harapan: A Cross-Sectional Study

Riona Sutanto; Vivien Puspitasari; Astra Dea Simanungkalit; Pricilla Yani Gunawan

doi:10.19166/lijn.v2i1.11012

Autor/innen

Riona Sutanto Universitas Pelita Harapan
Vivien Puspitasari Universitas Pelita Harapan
Astra Dea Simanungkalit Universitas Pelita Harapan
Pricilla Yani Gunawan Universitas Pelita Harapan

DOI:

https://doi.org/10.19166/lijn.v2i1.11012

Schlagworte:

Carpal Tunnel Syndrome, Body Mass Index, Obesity

Abstract

Introduction: Carpal Tunnel Syndrome (CTS) is one of the most common entrapment neuropathies, though its exact cause remains unclear. Obesity has been identified as a potential risk factor, but previous studies have reported inconsistent findings. This study aimed to analyze the association between Body Mass Index (BMI) and CTS among pre-clinical medical students at Universitas Pelita Harapan.

Methods: This cross-sectional study utilized the Boston Carpal Tunnel Syndrome Questionnaire (BCTQ) to assess symptom severity and functional status. Body weight and height were self-reported via questionnaire to calculate BMI. Bivariate analyses are used to examine the association statistically, followed by stratified analyses to assess potential confounding factors.

Results: A total of 201 participants met the inclusion and exclusion criteria for this study. Among them, 7.5% of the subjects presented with symptoms of CTS, and 5.0% experienced functional impairment. The association between BMI and CTS based on the severity of symptoms and functional status impairment was found to be significant (p = 0.004 and 0.049, respectively).

Conclusion: Higher BMI was significantly associated with an increased likelihood of CTS symptoms and functional impairment. Gender and a history of diabetes mellitus were identified as potential confounding factors.

Keywords: Carpal Tunnel Syndrome, Body Mass Index, Obesity

Literaturhinweise

1. Aboonq MS. Pathophysiology of carpal tunnel syndrome. Neurosciences (Riyadh). 2015 Jan;20(1):4–9.

2. Padua L, Coraci D, Erra C, Pazzaglia C, Paolasso I, Loreti C, et al. Carpal tunnel syndrome: clinical features, diagnosis, and management. Lancet Neurol. 2016 Nov;15(12):1273–84.

3. Saggar SK, Thaman RG, Mohan G, Kumar D. Mapping Neurophysiological Patterns in Carpal Tunnel Syndrome: Correlations With Tinel’s and Phalen’s Signs. Cureus. 2024 Apr;16(4):e58168.

4. Chang YW, Hsieh TC, Tzeng IS, Chiu V, Huang PJ, Horng YS. Ratio and difference of the cross-sectional area of median nerve to ulnar nerve in diagnosing carpal tunnel syndrome: a case control study. BMC Med Imaging. 2019 Jul 4;19(1):52.

5. Otelea MR, Nartea R, Popescu FG, Covaleov A, Mitoiu BI, Nica AS. The Pathological Links between Adiposity and the Carpal Tunnel Syndrome. Curr Issues Mol Biol. 2022 Jun 8;44(6):2646–63.

6. AlHussain AH, Alshahir AA, AlNaqa FH, Alsaygh EF, Alquwaiz IA, Alqahtani MS. Prevalence and Predictors of Carpal Tunnel Syndrome Symptoms Among Teachers in Riyadh: A Cross-Sectional Study. Cureus. 2023 Feb;15(2):e35040.

7. Callaghan BC, Gao L, Li Y, Zhou X, Reynolds E, Banerjee M, et al. Diabetes and obesity are the main metabolic drivers of peripheral neuropathy. Ann Clin Transl Neurol. 2018 Apr;5(4):397–405.

8. Rani M, Yadav N, Srivastava M, Jain A, Srivastava N, Yadav A, et al. An Evaluation of Variations in the Carpal Tunnel Dimensions of Adult Subjects in a Hospital-Based Population: An Ultrasonographic Cross-Sectional Study. Cureus. 2024 Mar;16(3):e56001.

9. Octaviana F, Safri YPAY, Wiratman W, Indrawati LA, Hakim M. Uji Validitas dan Reliabilitas Kuesioner Sindrom Terowongan Karpal Boston Versi Bahasa Indonesia. eJournal Kedokteran Indonesia (eJKI). 2022;10(1):18–25.

10. Skelly AC, Dettori JR, Brodt ED. Assessing bias: the importance of considering confounding. Evid Based Spine Care J. 2012 Feb;3(1):9–12.

11. Kurniaputri GA, Pinzon RT, Veronica V, Pramudita EA. Prevalensi dan Faktor Risiko Carpal Tunnel Syndrome pada Perawat. Jurnal Ilmu Kesehatan Masyarakat. 2022 Sep 7;11(05):411–6.

12. Furti Okliantoni Pratiwi, Herlina, Wasisto Utomo. Gambaran Keluhan Carpal Tunnel Syndrome (CTS) pada Pekerja Pengguna Komputer. HEALTH CARE: JURNAL KESEHATAN. 2022 Dec 31;11(2):403–10.

13. Hassan A, Beumer A, Kuijer PPFM, van der Molen HF. Work-relatedness of carpal tunnel syndrome: Systematic review including meta-analysis and GRADE. Health Sci Rep. 2022 Nov;5(6):e888.

14. Jackson R, Beckman J, Frederick M, Musolin K, Harrison R. Rates of Carpal Tunnel Syndrome in a State Workers’ Compensation Information System, by Industry and Occupation - California, 2007-2014. MMWR Morb Mortal Wkly Rep. 2018 Oct 5;67(39):1094–7.

15. Oka PKDWI, Utami S, Setiawan NCT, Tunjung IW. Hubungan Indeks Massa Tubuh dan Jenis Kelamin dengan Derajat Keparahan Carpal Tunnel Syndrome Di RSUD Kota Mataram. Nusantara Hasana Journal. 2023 Mar;2(10):20–7.

16. Bekele A, Abebe G, Hailu T, Fekadu T, Gebremickael A, Getachew T, et al. Prevalence and Associated Factors of Carpal Tunnel Syndrome Among Diabetic Patients in Arba Minch General Hospital, South West Ethiopia, 2021. Diabetes Metab Syndr Obes. 2022;15:983–93.

17. Salamh F, Habib SS, AlRouq F, Albarrak A, Al-Khlaiwi T, Khan A. Relationship of obesity indices with clinical severity and nerve conduction studies in females presenting with median nerve compression neuropathy at the wrist. J Family Med Prim Care. 2024 Apr;13(4):1291–5.

18. Hendriks SH, van Dijk PR, Groenier KH, Houpt P, Bilo HJ, Kleefstra N. Type 2 diabetes seems not to be a risk factor for the carpal tunnel syndrome: a case control study. BMC Musculoskelet Disord. 2014 Dec 14;15(1):346.