Anesthetic Management in Obese Patients Undergoing Laparoscopic Cholecystectomy: A Case Report
DOI:
https://doi.org/10.19166/med.v14i3.10152Λέξεις-κλειδιά:
Anesthesia management in laparoscopy, Laparoscopic complications, Laparoscopy, ObesityΠερίληψη
Background: Obesity is associated with various complications during general anesthesia, including apnea, hypoventilation, and challenges in intubation. In obese patients, these factors increase the anesthetic risks associated with laparoscopic cholecystectomy, a minimally invasive surgery performed to remove the gallbladder. This procedure is often indicated for gallstones causing inflammation, pain, or infection. Laparoscopic cholecystectomy involves small incisions, allowing most patients to recover quickly, return home the same day, and resume normal activities shortly thereafter. Compared to open cholecystectomy, the laparoscopic approach offers advantages such as faster recovery, reduced postoperative pain, and lower risk of complications.
Methods: A 43-year-old female patient with a body weight of 120 kg, height of 155 cm, and a BMI of 49.9 kg/m² (classified as obesity) was initially scheduled for an open cholecystectomy. However, intraoperative evaluation by the surgeon led to a decision to switch to laparoscopic cholecystectomy. Anesthesia was induced using a propofol syringe pump, fentanyl (150 mcg), and atracurium (40 mg) as a muscle relaxant. Intubation was performed with video laryngoscopy, using an endotracheal tube (ETT) with a cuff size of 7.
Result: During the operation, the patient's end-tidal CO2 (ETCO2) levels increased to 40 mmHg due to CO2 insufflation, leading to worsening respiratory acidosis. Complications such as these are common during laparoscopic procedures in obese patients and require timely management to prevent further deterioration.
Conclusions: The patient’s condition was stabilized by employing specific intraoperative strategies, including positioning in reverse Trendelenburg, mild hyperventilation, and applying positive end-expiratory pressure (PEEP). These measures successfully reduced ETCO2 levels, demonstrating the importance of tailored anesthetic and ventilatory management in obese patients undergoing laparoscopic cholecystectomy.
Αναφορές
1. Lin X, Li H. Obesity: epidemiology, pathophysiology, and therapeutics. Front Endocrinol (Lausanne). 2021;12:1–9. https://doi.org/10.3389/fendo.2021.706978
2. Zatońska K, Psikus P, Basiak-Rasała A, Stępnicka Z, Gaweł-Dabrowska D, Wołyniec M, et al. Obesity and chosen non-communicable diseases in PURE Poland cohort study. Int J Environ Res Public Health. 2021;18(5):1–10. https://doi.org/10.3390/ijerph18052701
3. Putri SMNK, Christina MM, Suhardin, Saverinus, Halimatunnisa M, Susanti I. Factors associated with obesity in adults in South East Asia. Int J Psychosoc Rehabil. 2020;24(7):7599-7607. 10.37200/IJPR/V24I7/PR2700728
4. Kaye AD, Lingle BD, Brothers JC, Rodriguez JR, Morris AG, Greeson EM, et al. The patient with obesity and super-super obesity: perioperative anesthetic considerations. Saudi J Anaesth. 2022;16(3):332. https://doi.org/10.4103/sja.sja_235_22
5. Jirapinyo P, Thompson C. Sedation challenges: obesity and sleep apnea. Gastrointest Endosc Clin N Am. 2016;26(3):527–37. https://doi.org/10.1016/j.giec.2016.03.001
6. Yamochi S, Kinoshita M, Sawa T. Anesthetic management of a severely obese patient (body mass index 70.1 kg/m²) undergoing giant ovarian tumor resection: a case report. J Med Case Rep. 2022;16(1):1–4. https://doi.org/10.1186/s13256-022-03383-x
7. Willis S, Bordelon GJ, Rana MV. Perioperative pharmacologic considerations in obesity. Anesthesiol Clin. 2017;35(2):247–57. https://doi.org/10.1016/j.anclin.2017.01.010
8. Afors K, Centini G, Murtada R, Castellano J, Meza C, Wattiez A. Obesity in laparoscopic surgery. Best Pract Res Clin Obstet Gynaecol. 2015;29(4):554–64.
9. Brondeel K, Lakatta A, Torres G, Hurley J, Kunik I, Haney K, et al. Physiologic and pharmacologic considerations in morbid obesity and bariatric anesthesia. Saudi J Anaesth. 2022;16(3):306. https://doi.org/10.1016/j.bpobgyn.2015.02.001
10. Lim JU, Lee JH, Kim JS, Hwang YI, Kim TH, Yong S, et al. Comparison of World Health Organization and Asia-Pacific body mass index classifications in COPD patients. Int J Chron Obstruct Pulmon Dis. 2017;12:2465–75. https://doi.org/10.2147/copd.s141295
11. Jonas E, Biccard B. Obesity and surgery in general. S Afr J Surg. 2021;59(2):38–40. http://dx.doi.org/10.17159/2078-5151/2021/v59n2a3699
12. Bass G, Gilani SNS, Walsh TN. Validating the 5Fs mnemonic for cholelithiasis: time to include family history. Postgrad Med J. 2013;89(1057):638–41. https://doi.org/10.1136/postgradmedj-2012-131341
13. Seyni-Boureima R, Zhang Z, Antoine MMLK, Antoine-Frank CD. A review on the anesthetic management of obese patients undergoing surgery. BMC Anesthesiol. 2022;22(1):1–13. https://doi.org/10.1186/s12871-022-01579-8
14. Kaye A, Lingle B, Brothers J, Rodriguez J, Morris A, Greeson E, et al. The patient with obesity and super-super obesity: perioperative anesthetic considerations. Saudi J Anaesth. 2022;16(3):332. https://doi.org/10.4103/sja.sja_235_22
15. Saoraya J, Vongkulbhisal K, Kijpaisalratana N, Lumlertgul S, Musikatavorn K, Komindr A. Difficult airway predictors were associated with decreased use of neuromuscular blocking agents in emergency airway management: a retrospective cohort study in Thailand. BMC Emerg Med. 2021;21(1):1–9. https://doi.org/10.1186/s12873-021-00434-2
16. Mahmoud M, Hasanin AM, Mostafa M, Alhamade F, Abdelhamid B, Elsherbeeny M. Evaluation of super-obesity and super-super-obesity as risk factors for difficult intubation in patients undergoing bariatric surgery. Surg Obes Relat Dis. 2021;17(7):1279–85. https://doi.org/10.1016/j.soard.2021.03.028
17. Lukosiute A, Karmali A, Cousins JM. Anaesthetic preparation of obese patients: current status on optimal work-up. Curr Obes Rep. 2017;6(3):229–37. https://doi.org/10.1007/s13679-017-0268-5
18. Keus F, De Jong JAF, Gooszen HG, Van Laarhoven CJHM. Laparoscopic versus small-incision cholecystectomy for patients with symptomatic cholecystolithiasis. Cochrane Database Syst Rev. 2006;(4):CD006229. https://doi.org/10.1002/14651858.cd006229
19. Scheib SA, Tanner E, Green IC, Fader AN. Laparoscopy in the morbidly obese: physiologic considerations and surgical techniques to optimize success. J Minim Invasive Gynecol. 2014;21(2):182–95. https://doi.org/10.1016/j.jmig.2013.09.009
20. Tiong L, Oh J. Safety and efficacy of a laparoscopic cholecystectomy in the morbid and super obese patients. HPB (Oxford). 2015;17(7):600–4. https://doi.org/10.1111/hpb.12415
21. Amornyotin S. Anesthetic management for laparoscopic cholecystectomy. Endoscopy. 2013;45(Suppl 2):E248. http://dx.doi.org/10.5772/52742
22. Bandewar A, Naik S, Kokne M, Kaur S. Comparison of the efficacy of combined epidural anesthesia with general anaesthesia alone to attenuate hemodynamic responses and perioperative analgesia in laparoscopic cholecystectomy patients. Int J Res Med Sci. 2019;7(7):2696–701. https://doi.org/10.18203/2320-6012.ijrms20192902
23. Zhu J, Zhang XR, Yang H. Effects of combined epidural and general anesthesia on intraoperative hemodynamic responses, postoperative cellular immunity, and prognosis in patients with gallbladder cancer. Medicine (Baltimore). 2017;96(10):e6218. https://doi.org/10.1097/md.0000000000006137
24. Nightingale CE, Margarson MP, Shearer E, Redman JW, Lucas DN, Cousins JM, et al. Peri-operative management of the obese surgical patient 2015: Association of Anaesthetists of Great Britain and Ireland Society for Obesity and Bariatric Anaesthesia. Anaesthesia. 2015;70(7):859–76. https://doi.org/10.1111/anae.13101
25. Couture EJ, Provencher S, Somma J, Lellouche F, Marceau S, Bussières JS. Effect of position and positive pressure ventilation on functional residual capacity in morbidly obese patients: a randomized trial. Can J Anaesth. 2018;65(5):522–8. https://doi.org/10.1007/s12630-018-1050-1
26. Kwak HJ, Jo YY, Lee KC, Kim YB, Shinn HK, Kim JY. Acid-base alterations during laparoscopic abdominal surgery: a comparison with laparotomy. Br J Anaesth. 2010;105(4):442–7. https://doi.org/10.1093/bja/aeq185
27. Hassan N, Jan R, Lone AQ, Zahoor SA. Effect of pneumoperitoneum with carbon dioxide in abdominal laparoscopic surgeries on hemodynamic and arterial blood gas parameters. Int J Adv Res. 2019;7(5):106–16. https://dx.doi.org/10.21474/IJAR01/9009
28. Mazzinari G, Diaz-Cambronero O, Alonso-Iñigo JM, Garcia-Gregorio N, Ayas-Montero B, Ibañez JL, et al. Intraabdominal pressure-targeted positive end-expiratory pressure during laparoscopic surgery: an open-label, nonrandomized, crossover, clinical trial. Anesthesiology. 2020;132(4):667–77. https://doi.org/10.1097/aln.0000000000003146
Λήψεις
Δημοσιευμένα
Πώς να δημιουργήσετε Αναφορές
Τεύχος
Ενότητα
Άδεια
Πνευματική ιδιοκτησία (c) 2025 Insan Aqid Pakardian, Dewa Ayu Mas Shintya Dewi

Αυτή η εργασία είναι αδειοδοτημένη υπό το Creative Commons Attribution-ShareAlike 4.0 International License.
Authors who publish with this journal agree to the following terms:
1) Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License (CC-BY-SA 4.0) that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
2) Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
3) Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website). The final published PDF should be used and bibliographic details that credit the publication in this journal should be included.


