The Relationship Between Brain Tumor And Sleep Components (Psqi) In Siloam Hospitals Lippo Village 2015-2018

Hans Christian Uranus, Julius July

Abstract


Introduction: Brain tumor can cause symptoms such as headache and seizure which might reduce sleep quality. Currently, sleep quality in brain tumor patients aren’t getting much attention. This study’s purpose is to determine the effect of brain tumor to sleep quality and its components in patients.

Methods: The design of this study is a retrospective cohort, and it is done in Siloam Hospitals Lippo Village and Paviliun Umum Rumah Sakit Siloam from January-April 2019 with sample population consisting of brain tumor patients from age 19 until 59 years old. The sample amount is 29 subjects. PSQI is used to assess sleep quality and components. Data analysis uses the SPSS version 24.0 software and statistical  analysis using chi2.

Result: Brain tumor patients have worse sleep quality compared to the control, with 26 patients (89.7 %) having bad sleep quality. For the control, there are only 18 people (62.1%) who have bad sleep quality. The relationship between brain tumor and sleep quality have a p value of 0.032 and relative risk (RR) of 3,7. Brain tumor has a significant relationship with sleep latency (p value 0,015) and daytime dysfunction (p value 0,02)

Conclusion: The relationship between brain tumor and sleep quality in brain tumor patients of Siloam Hospitals Lippo Village and Paviliun Umum Rumah Sakit Siloam, which was measured with the PSQI questionnaire is significant. Brain tumor also has a significant relation with sleep latency and daily dysfunction.


Keywords


Brain tumor, PSQI, Sleep components, Sleep quality.



DOI: http://dx.doi.org/10.19166/med.v7i4.2384

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References


Butowski NA. Epidemiology and Diagnosis of Brain Tumors. Contin Lifelong Learn Neurol [Internet]. 2015 Apr [cited 2018 Sep 6];21(2 Neuro-oncology):301–13. Available from: http://www.ncbi.nlm.nih.gov/pubmed/25837897

Comelli I, Lippi G, Campana V, Servadei F, Cervellin G. Clinical presentation and epidemiology of brain tumors firstly diagnosed in adults in the Emergency Department: a 10-year, single center retrospective study. Ann Transl Med [Internet]. 2017 Jul [cited 2018 Sep 16];5(13):269. Available from: http://www.ncbi.nlm.nih.gov/pubmed/28758095

Armstrong TS, Shade MY, Breton G, Gilbert MR, Mahajan A, Scheurer ME, et al. Sleep-wake disturbance in patients with brain tumors. Neuro Oncol. 2017;19(3):323–35.

Ostrom QT, Gittleman H, Liao P, Vecchione-Koval T, Wolinsky Y, Kruchko C, et al. CBTRUS Statistical Report: Primary brain and other central nervous system tumors diagnosed in the United States in 2010–2014. Neuro Oncol [Internet]. 2017;19(suppl_5):v1–88. Available from: http://academic.oup.com/neuro-oncology/article/19/suppl_5/v1/4596648

de Robles P, Fiest KM, Frolkis AD, Pringsheim T, Atta C, St Germaine-Smith C, et al. The worldwide incidence and prevalence of primary brain tumors: a systematic review and meta-analysis. Neuro Oncol [Internet]. 2015 Jun [cited 2018 Sep 6];17(6):776–83. Available from: http://www.ncbi.nlm.nih.gov/pubmed/25313193

Robertson ME, McSherry F, Herndon JE, Peters KB. Insomnia and its associations in patients with recurrent glial neoplasms. Springerplus. 2016;5(1):1–5.

Jeon MS, Dhillon HM, Agar MR. Sleep disturbance of adults with a brain tumor and their family caregivers: A systematic review. Neuro Oncol. 2017;19(8):1035–46.

Aman RA, Soenarya MF, Andriani R, Aninditha T, Munandar A, Tadjoedin H, et al. Pedoman Nasional Pelayanan Kedokteran Tumor Otak [Internet]. Kementerian Kesehatan Republik Indonesia; Available from: http://kanker.kemkes.go.id/guidelines/PNPKOtak.pdf

Endeshaw Y. Aging, subjective sleep quality, and health status: the global picture. Sleep [Internet]. 2012 Aug 1 [cited 2019 Jul 4];35(8):1035–6. Available from: http://www.ncbi.nlm.nih.gov/pubmed/22851799

Peltzer K, Pengpid S. Sleep duration, sleep quality, body mass index, and waist circumference among young adults from 24 low- and middle-income and two high-income countries. Int J Environ Res Public Health. 2017;14(6).

Leistner SM, Klotsche J, Dimopoulou C, Athanasoulia P, Roemmler-zehrer J, Pieper L, et al. Reduced sleep quality and depression associate with decreased quality of life in patients with pituitary adenomas. 2015;

Pickering L, Jennum P, Gammeltoft S, Poulsgaard L, Feldt-rasmussen U, Klose M. Sleep – wake and melatonin pattern in craniopharyngioma patients. 2014;(2).

Shrivastava D, Jung S, Saadat M, Sirohi R, Crewson K. How to interpret the results of a sleep study. 2014;1:1–4.

Kristen L. Knutson P, Armand M. Ryden M, Bryce A. Mander B. Role of Sleep Duration and Quality in the Risk and Severity of Type 2 Diabetes Mellitus. Arch Intern Med [Internet]. 2006; Available from: https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/410883

Nagai M, Hoshide S, Kario K. Sleep Duration as a Risk Factor for Cardiovascular Disease- a Review of the Recent Literature. 2010;54–61.

Roeser K, Eichholz R, Schwerdtle B, Schlarb AA, Kübler A. Relationship of sleep quality and health-related quality of life in adolescents according to self- and proxy ratings: a questionnaire survey. Front psychiatry [Internet]. 2012 [cited 2018 Oct 31];3:76. Available from: http://www.ncbi.nlm.nih.gov/pubmed/22969731

Opp MR, Krueger JM. Sleep and Immunity: A Growing Field with Clinical Impact. [cited 2018 Sep 16]; Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685944/pdf/nihms-694135.pdf

Hong JS, Tian J, Wu LH. The influence of chemotherapy-induced neurotoxicity on psychological distress and sleep disturbance in cancer patients. Curr Oncol [Internet]. 2014 Aug [cited 2018 Sep 21];21(4):174–80. Available from: http://www.ncbi.nlm.nih.gov/pubmed/25089099

Jain S V., Glauser TA. Effects of epilepsy treatments on sleep architecture and daytime sleepiness: An evidence-based review of objective sleep metrics. Epilepsia [Internet]. 2014 Jan [cited 2018 Sep 21];55(1):26–37. Available from: http://www.ncbi.nlm.nih.gov/pubmed/24299283


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MEDICINUS is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License. Copyright © Fakultas Kedokteran | Universitas Pelita Harapan | Lippo Karawaci, Tangerang, Indonesia, 15811 . All rights reserved. p-ISSN 1978-3094 | e-ISSN 2622-6995